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CLARIPEN - 500MG

CLARIPEN
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COST KES 2131.50
Pack Size 14

Generic Name CLARITHROMYCIN
Class Name MACROLIDES

Consumer Information about this Product

Class Details

ACT BY BINDING TO BACTERIAL RIBOSOMES TO INTERFERE WITH PROTEIN SYNTHESIS. ERYTHROMYCIN HAS A SPECTRUM SIMILAR TO PENICILLIN AND IS USED AS AN ALTERNATIVE IN PENICILLIN-ALLERGIC PATIENTS. AZITHROMYCIN HAS LESS ACTIVITY AGAINST GRAM-POSITIVES BUT MORE AGAINST GRAM-NEGATIVES THAN ERYTHROMYCIN. AZITHROMYCIN AND CLARITHROMYCIN CAUSE FEWER GI SIDE EFFECTS THAN ERYTHROMYCIN.


STREPTOCOCCAL PHARYNGITIS. SINUSITIS. OTITIS MEDIA. CHEST INFECTIONS. SKIN AND SOFT-TISSUE INFECTIONS. ADJUNCT IN ERADICATION OF H PYLORI. 250-500MG BD, WITH OR WITHOUT FOOD.
Category C: Either animal-reprodcution studies have shown adverse effects to fetus but studies in women have not been done/are not avialable or studies in animals and in women are not available. Use only when potential benefit justifies potential risk to
HYPERSENSITIVITY TO MACROLIDES.
SUBSTRATE AND INHIBITOR OF CYP3A3/4. INDUCERS EG RIFAMPICIN DECREASE EFFECT WHILE INHIBITORS EG KETOCONAZOLE INCREASE EFFECT OF SAQUINAVIR
NAUSEA. VOMITING. DIARRHOEA. ABDOMINAL DISCOMFORT. ALLERGIC REACTIONS. DYSPEPSIA. TASTE AND SMELL DISTURBANCES.JAUNDICE. KIDNEY FAILURE.

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